C1623 Emperor Grade Divine Medicine Quasi Emperor Realm
To refine a Imperial Grade Pill, the Imperial Panacea has to be the main ingredient. This was a law.
Even an existence above Great Emperor would not be able to break this law.
However, Emperor Grade Low Level s could only be encountered by chance and not sought. If a Master of Ancient Medicine wanted to obtain one, the difficulty would be equivalent to ascending to the heavens.
Furthermore